Min Zhang

Executive Summary & Candidate Overview

Min is a seasoned professional in drug discovery, boasting over 12 years of experience post-PhD. With expertise in small molecule, oligonucleotides, and gene therapeutic modalities, Min has excelled in project and group leadership, target identification and validation, toxicity studies, and PK/PD modeling. With a strong background in lung and gastrointestinal research, Min brings valuable skills in in vitro and in vivo disease modeling, along with excellent communication and organizational abilities.

Accomplishments and Key Skills

Min's key accomplishments and skills include:

• Project and group leadership in fibrosis and inflammatory diseases research.

• Early target identification and validation.

• Expertise in in vitro and in vivo disease modeling.

• Proficiency in PK/PD modeling and toxicity studies.

• Excellent communication, organization, and presentation skills.

• Strong background in lung and gastrointestinal research, with several publications in high-quality journals.

Location and Travel

• Open to: On-site roles.

• Remote Roles: Willing to consider opportunities based on specific position requirements.

• Compensation Seeking: Open to discussing compensation details upon scheduling a meeting.

• Position Seeking: Seeking leadership roles in drug discovery.

Work Experience

1. Assistant Director (Drug Discovery) - Ionis Pharmaceuticals at San Diego (February 2017 – Present)

   • Project leader responsible for managing direct reports, cross-functional teams, and external collaborations.

   • Led targets identification and validation for fibrosis and inflammatory diseases research.

   • Contributed to IND filing and toxicity studies for oligonucleotides and SARs.

2. Research Scientist II - Vertex Pharmaceuticals at San Diego (June 2014 – February 2017)

   • Supported drug discovery efforts for Cystic Fibrosis.

   • Developed novel cell culture protocols and assays for small molecule drug screening.

   • Conducted high throughput screening and single-cell RNA-seq analysis.

3. Postdoc Research Associate - Pharmacology, University of Illinois at Chicago (2011 – 2014)

   • Conducted research on stem cell and gene therapy for bacterial-induced lung injury.

   • Analyzed endothelial cell regeneration after lung inflammation and injury.

   • Investigated G proteins in embryonic stem cell and iPSCs endothelial differentiation.

Education

• Ph.D. in Cellular and Integrative Physiology Indiana University, August 2003 to October 2009

• M.S. in Physiology Capital University of Medical Science, September 2000 to May 2003

• B.S. in Dentistry ShanXi Medical University, September 1995 to July 2000